Dr. Gaurav Jhaa Blogs

Isomers hosting three epoxides prefer axial orientation by a huge margin (>40kcal/mol) despite having severe steric problems.  Among the two axial isomers, the ‘all-cis’ structure 1B is less stable than the cis-trans hy-brid 1A though the C-C bond alternation is moderate in 1B compared to 1A .  This reduced bond alternation in 1B along with the fact that it also has a planar cyclohexane ring unlike 1A suggests the possibility of cyclic conjuga-tion à la aromatic delocalization in 1B ; however, it is not dominating the energetics compared to the repulsive O…..O interactions. The splaying of cis oxygen atoms that adversely affect C-C bonding is less in 1B (0.600Å) than 1A (0.624Å), facilitating cyclic delocalization in ‘all-cis’ form.  Overlap Control of Conformations Bonding in epoxides is usually explained by two classical models, though both have their own drawbacks.  The popular bent ‘banana bond’ model of Coulson is borrowed from cyclopropane that uses isovalent hybridiz

  Identify your business idea: Think about what products or services you want to offer, and how you can differentiate yourself from competitors in the market. Conduct market research: Find out if there is a demand for your product or service, who your target audience is, and what your competition looks like. Create a business plan: Develop a plan that outlines your business goals, strategies for reaching those goals, and financial projections. A business plan will help you stay on track and give you a roadmap to follow. Determine your legal structure: Decide what type of legal entity you want to form, such as a sole proprietorship, partnership, LLC, or corporation. Each structure has its own advantages and disadvantages, so do your research and choose the one that best fits your needs. Register your business: Register your business with your state or local government, obtain any necessary licenses and permits, and register for taxes. Secure funding: Determine how much m

  The future of AI is expected to be transformative in various fields, from healthcare to transportation, finance, manufacturing, and beyond. Here are some potential developments that could shape the future of AI: Continued progress in machine learning: The development of more advanced machine learning algorithms will likely drive significant AI advancements. This includes deep learning, reinforcement learning, and other techniques that enable machines to learn from data and improve over time. Increased automation: As AI systems become more sophisticated, they can take on increasingly complex tasks, likely leading to greater automation in various industries. This could result in significant increases in efficiency, productivity, and job displacement. Improved natural language processing: AI systems are expected to become much better at understanding and responding to natural language, which could have significant implications for customer service, chatbots, and other applicati